TCP1 alpha/CCTA anticorps (C-Term)
Aperçu rapide pour TCP1 alpha/CCTA anticorps (C-Term) (ABIN2789569)
Antigène
Voir toutes TCP1 alpha/CCTA (TCP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Séquence
- HNEAQVNPER KNLKWIGLDL SNGKPRDNKQ AGVFEPTIVK VKSLKFATEA
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
-
Attributs du produit
- This is a rabbit polyclonal antibody against TCP1. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 556 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
-
Autre désignation
- TCP1
-
Sujet
-
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.
Alias Symbols: CCT-alpha, CCT1, CCTa, D6S230E, TCP-1-alpha
Protein Interaction Partner: FUS, ERLIN2, HUWE1, CBFA2T2, UBC, TP53, NEDD1, VHL, TUBG1, SUMO2, LGALS3BP, CDC20, STAU1, INPP5K, CDC5L, VRK2, PPP4C, COPA, COPG1, USP9X, PARK2, FBXO6, YWHAQ, UBD, FBXW4, FBXO46, STK25, HDAC6, HDAC3, NPM1, ILK, CDK5, CDK2, PAN2, US3, FAM86B2, CFAP52, METT
Protein Size: 556 -
Poids moléculaire
- 61 kDa
-
ID gène
- 6950
-
NCBI Accession
- NM_030752, NP_110379
-
UniProt
- P17987
Antigène
-